Below are the studies that informed this product:
1. Ohta S. Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine. Pharmacol Ther 2014, 144:1-11.
2. Ohsawa I, Ishikawa M, Takahashi K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007, 13:688-694.
3. Hara F, Tatebe J, Watanabe I, et al. Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells. Circ J 2016, 80:2037-2046.
4. Nakao A, Toyoda Y, Sharma P, et al. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr 2010, 46:140-149.
5. LeBaron TW, Singh RB, Fatima G, et al. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes 2020, 13:889-896.
6. Song G, Li M, Sang H, et al. Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome. J Lipid Res 2013, 54:1884-1893.
7. Dobashi S, Takeuchi K, Koyama K. Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males. Med Gas Res 2020, 10:21-26.
8. Sim M, Kim CS, Shon WJ, et al. Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial. Sci Rep 2020, 10:12130.
9. Kajiyama S, Hasegawa G, Asano M, et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res 2008, 28:137-143.
10. Todorovic N, Fernandez-Landa J, Santibanez A, et al. The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis. Pharmaceuticals (Basel) 2023, 16.
11. Ishibashi T, Kawamoto K, Matsuno K, et al. Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial. PLoS One 2020, 15:e0233484.
12. Sakai T, Sato B, Hara K, et al. Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag 2014, 10:591-597.
13. Todorovic N, Zanini D, Stajer V, et al. Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers. Food Sci Nutr 2021, 9:5139-5145.
14. Zanini D, Todorovic N, Korovljev D, et al. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Exp Gerontol 2021, 155:111574.
15. Aoki K, Nakao A, Adachi T, et al. Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Med Gas Res 2012, 2:12.
16. Botek M, Krejci J, McKune AJ, et al. Hydrogen Rich Water Improved Ventilatory, Perceptual and Lactate Responses to Exercise. Int J Sports Med 2019, 40:879-885.
17. Botek M, Krejci J, McKune A, et al. Hydrogen Rich Water Consumption Positively Affects Muscle Performance, Lactate Response, and Alleviates Delayed Onset of Muscle Soreness After Resistance Training. J Strength Cond Res 2022, 36:2792-2799.
18. LeBaron TW, Larson AJ, Ohta S, et al. Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study. J Lifestyle Med 2019, 9:36-43.
19. Mikami T, Tano K, Lee H, et al. Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study (1). Can J Physiol Pharmacol 2019, 97:857-862.
20. Da Ponte A, Giovanelli N, Nigris D, Lazzer S. Effects of hydrogen rich water on prolonged intermittent exercise. J Sports Med Phys Fitness 2018, 58:612-621.
21. Zanini D, Todorovic N, Korovljev D, et al. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Experimental Gerontology 2021, 155:111574.