Benefits
Stress, dietary factors, and an imbalance of microorganisms in the gut can cause occasional gastrointestinal discomfort. The ingredients in Gastro Calm support a healthy gastric mucosa and microbial balance, and may be helpful for occasional heartburn, bloating, or upset stomach.
Bottle contains 60 capsules (15-day supply)
Caution: If you are pregnant, nursing, or on medication, consult with your healthcare practitioner.
- Supports health of the stomach lining and gastric microbial balance
- Vegan and non-GMO; free of gluten, dairy, and soy
- A blend of vitamin C, zinc-L-carnosine, and botanical extracts
Key Ingredients
Zinc-L-carnosine
Zinc caronsine is a compound made up of the mineral zinc and amino acid carnosine. Research suggests zinc carnosine has protective effects on the gut mucosal lining and promotes microbial balance. Zinc carnosine also has antioxidant and anti-inflammatory effects in laboratory studies.
Mastic gum (Pistacia lentiscus)
Mastic gum is a resinous substance derived from a Mediterranean shrub whose stems, leaves, and fruit contain antioxidant, anti-inflammatory, and antimicrobial phytochemicals.
GutGard®
GutGard® is a flavonoid-rich extract of licorice root (deglycyrrhizinated licorice; Glycyrrhiza glabra). Studies suggest licorice root extract promotes gastric microbial balance. Studies on mastic gum, licorice root extract, and methylmethionine sulfonium chloride suggest they promote gastric microbial balance.
Methylmethionine sulfonium chloride
Methylmethionine sulfonium chloride is a derivative of the amino acid methionine, is found in cabbage and other cruciferous vegetables. Laboratory studies on methylmethionine sulfonium chloride suggest it promotes gastric mucosal cell function.
Frequently Asked Questions
Is Gastro Calm gluten-free? Allergen-free?
Gastro Calm is not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. It is produced in a Good Manufacturing Practices (GMP) facility that processes other ingredients containing these allergens.
What research went into this product?
Below are the studies that informed this product:
1. Hewlings S, Kalman D. A Review of Zinc-L-Carnosine and Its Positive Effects on Oral Mucositis, Taste Disorders, and Gastrointestinal Disorders. Nutrients 2020, 12.
2. Milia E, Bullitta SM, Mastandrea G, et al. Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection. Antibiotics (Basel) 2021, 10.
3. Huwez FU, Thirlwell D, Cockayne A, Ala'Aldeen DA. Mastic gum kills Helicobacter pylori. N Engl J Med 1998, 339:1946.
4. Puram S, Suh HC, Kim SU, et al. Effect of GutGard in the Management of Helicobacter pylori: A Randomized Double Blind Placebo Controlled Study. Evid Based Complement Alternat Med 2013, 2013:263805.
5. Ullah H, Di Minno A, Santarcangelo C, et al. Vegetable Extracts and Nutrients Useful in the Recovery from Helicobacter pylori Infection: A Systematic Review on Clinical Trials. Molecules 2021, 26.
6. Cheney G. Vitamin U therapy of peptic ulcer. Calif Med 1952, 77:248-252.
7. Ichikawa T, Ito Y, Saegusa Y, et al. Effects of combination treatment with famotidine and methylmethionine sulfonium chloride on the mucus barrier of rat gastric mucosa. J Gastroenterol Hepatol 2009, 24:488-492.
8. Watanabe T, Ohara S, Miyazawa S, et al. Augmentative effects of L-cysteine and methylmethionine sulfonium chloride on mucin secretion in rabbit gastric mucous cells. J Gastroenterol Hepatol 2000, 15:45-52.
