Benefits
Mega EPA is a pure, high-dose omega-3 fish oil supplement sourced from the waters of Peru and Chile, which provides 1000 mg omega-3 fatty acids in each softgel. The omega-3 fatty acids DHA and EPA are important for long-term healthy brain and nervous system function. EPA and DHA are structural components of cell membranes in the brain and retina, and help to regulate mood, cognition, and the body's inflammatory response.
Bottle contains 60 softgels (60-day supply)
Caution: If you are pregnant, nursing, or on medication, consult with your healthcare practitioner.
WARNING: Consult your health care practitioner before use if you are taking blood thinning medication or are planning to have surgery.
- Each softgel contains 662 mg EPA and 250 mg DHA
- Promotes a balanced inflammatory response
- Supports healthy brain and nervous system function
- Supports cardiovascular health
- Non-GMO; does not contain gluten, dairy, or soy
Key Ingredients
Fish oil concentrate
These softgels contain more EPA and DHA than typical fish oil supplements, with 662 mg EPA and 250 mg DHA in each softgel. The oil is derived from sustainable wild-caught anchovy, sardine, and mackerel fish from warm waters off the coast of Peru and Chile and processed in Norway. Mega EPA provides omega-3 fatty acids in their triglyceride form, the form in which they naturally occur in fish and microalgae.
Frequently Asked Questions
What steps are taken to ensure freshness and remove impurities?
The fish oil is molecularly distilled and filtered to maximize removal of heavy metals, pesticides, PCBs, and other contaminants. Vitamin E (as tocotrienols) is added to prevent oxidation.
How do I know whether I should take DHA+EPA Purity or Mega EPA?
For most healthy people, the dose of 250 mg/day DHA and EPA derived from algae in DHA+EPA Purity is appropriate to prevent omega-3 insufficiency. However, some people require a higher dose. Mega EPA can be used when higher levels of supplementation are required than could be met with an algae-based product, or if your physician recommends a higher dose for a health concern.
How can I test my omega 3 fatty acid levels?
You can test your omega-3 index at home with this kit.
What should my omega-3 index levels be?
Your omega-3 index should be between 6% and 9%.
Is Mega EPA gluten-free?
Yes. Mega EPA does not contain wheat, gluten, soy, milk, egg, tree nut or sesame ingredients. It is produced in a Good Manufacturing Practices (GMP) facility that processes other ingredients containing these allergens. Mega EPA contains fish.
Is Mega EPA vegan?
No. The softgels contain bovine gelatin.
What research went into this product?
Below are the studies that informed this product:
1. von Schacky C. Importance of EPA and DHA Blood Levels in Brain Structure and Function. Nutrients 2021, 13.
2. Office of Dietary Supplements, National Institutes of Health. Omega-3 Fatty Acids. Fact Sheet for Health Professionals [https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/]
3. Li X, Bi X, Wang S, et al. Therapeutic Potential of omega-3 Polyunsaturated Fatty Acids in Human Autoimmune Diseases. Front Immunol 2019, 10:2241.
4. Gioxari A, Kaliora AC, Marantidou F, Panagiotakos DP. Intake of omega-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: A systematic review and meta-analysis. Nutrition 2018, 45:114-124 e114.
5. Chen X, Hong S, Sun X, et al. Efficacy of fish oil and its components in the management of psoriasis: a systematic review of 18 randomized controlled trials. Nutr Rev 2020, 78:827-840.
6. Duarte-Garcia A, Myasoedova E, Karmacharya P, et al. Effect of omega-3 fatty acids on systemic lupus erythematosus disease activity: A systematic review and meta-analysis. Autoimmun Rev 2020, 19:102688.
7. AlAmmar WA, Albeesh FH, Ibrahim LM, et al. Effect of omega-3 fatty acids and fish oil supplementation on multiple sclerosis: a systematic review. Nutr Neurosci 2019:1-11.
8. Grosso G, Galvano F, Marventano S, et al. Omega-3 fatty acids and depression: scientific evidence and biological mechanisms. Oxid Med Cell Longev 2014, 2014:313570.
9. DiNicolantonio JJ, O'Keefe JH. The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders. Nutrients 2020, 12.
10. Su KP, Tseng PT, Lin PY, et al. Association of Use of Omega-3 Polyunsaturated Fatty Acids With Changes in Severity of Anxiety Symptoms: A Systematic Review and Meta-analysis. JAMA Netw Open 2018, 1:e182327.
11. Mocking RJ, Harmsen I, Assies J, et al. Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. Transl Psychiatry 2016, 6:e756
12. Martins JG. EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J Am Coll Nutr 2009, 28:525-542.